N-(4-氯苯基)-2-硝基苯甲酰胺合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate P=750.075 Torr;
参考文献
Kakuta, Hiroki; Zheng, Xiaoxia; Oda, Hiroyuki; Harada, Shun; Sugimoto, Yukio; Sasaki, Kenji; Tai, Akihiro
Journal of Medicinal Chemistry, 2008 , vol. 51, # 8 p. 2400 - 2411
反应条件
triethylamine in dichloromethane
T=20°C;
参考文献
Kakuta, Hiroki; Zheng, Xiaoxia; Oda, Hiroyuki; Harada, Shun; Sugimoto, Yukio; Sasaki, Kenji; Tai, Akihiro
Journal of Medicinal Chemistry, 2008 , vol. 51, # 8 p. 2400 - 2411
反应条件
N-ethyl-N,N-diisopropylamine; HATU in N,N-dimethyl-formamide
T=20°C;
参考文献
Kauppi, Anna M.; Andersson, C. David; Norberg, Henrik A.; Sundin, Charlotta; Linusson, Anna; Elofsson, Mikael
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 22 p. 6994 - 7011
反应条件
1: SOCl2; DMF / CH2Cl2 / 20 °C
2: NEt3 / CH2Cl2 / 20 °C
View Scheme
参考文献
Chou, Yuo-Ling; Davey, David D.; Eagen, Keith A.; Griedel, Brian D.; Karanjawala, Rushad; Phillips, Gary B.; Sacchi, Karna L.; Shaw, Kenneth J.; Wu, Shung C.; Lentz, Dao; Liang, Amy M.; Trinh, Lan; Morrissey, Michael M.; Kochanny, Monica J.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 507 - 511
反应条件
titanium tetrachloride; zinc in tetrahydrofuran
Heating;
参考文献
Shi, Daqing; Rong, Liangce; Wang, Juxian; Zhuang, Qiya; Wang, Xiangshan; Hu, Hongwen
Synthetic Communications, 2004 , vol. 34, # 10 p. 1759 - 1765
