5-甲氧基-1,2,3,4-四氢萘-1-胺盐酸盐合成路线 （共 4 条）
参考文献
Bayer Aktiengesellschaft
Patent: US4868331 A1, 1989 ;
反应条件
palladium on activated charcoal; hydrogen in methanol; chloroform
T=25°C; 20 h;
参考文献
Akbaba, Yusuf; Akincioglu, Akin; Goecer, Huelya; Goeksu, Sueleyman; Guelcin, Ilhami; Supuran, Claudiu T.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2014 , vol. 29, # 1 p. 35 - 42
反应条件
1: sodium tetrahydroborate / methanol / 3 h / 0 - 25 °C
2: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 14 h / 0 - 25 °C / |Inert atmosphere
3: palladium on activated charcoal; hydrogen / methanol; chloroform / 20 h / 25 °C
View Scheme
参考文献
Akbaba, Yusuf; Akincioglu, Akin; Goecer, Huelya; Goeksu, Sueleyman; Guelcin, Ilhami; Supuran, Claudiu T.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2014 , vol. 29, # 1 p. 35 - 42
反应条件
1: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 14 h / 0 - 25 °C / |Inert atmosphere
2: palladium on activated charcoal; hydrogen / methanol; chloroform / 20 h / 25 °C
View Scheme
参考文献
Akbaba, Yusuf; Akincioglu, Akin; Goecer, Huelya; Goeksu, Sueleyman; Guelcin, Ilhami; Supuran, Claudiu T.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2014 , vol. 29, # 1 p. 35 - 42
