4-(5-溴-2-噻吩)苯甲腈合成路线 （共 2 条）
反应条件
potassium fluoride; silver nitrate; PdCl2(PPh)3 in dimethyl sulfoxide
T=100°C; 8 h;
参考文献
Kobayashi, Kei; Sugie, Atsushi; Takahashi, Masabumi; Masui, Kentaro; Mori, Atsunori
Organic Letters, 2005 , vol. 7, # 22 p. 5083 - 5085
反应条件
bromine in 1,2-dichloro-ethane
T=20°C; 2.5 h;
参考文献
Chaires, Jonathan B.; Ren, Jinsong; Hamelberg, Donald; Kumar, Arvind; Pandya, Vandna; Boykin, David W.; Wilson, W. David
Journal of Medicinal Chemistry, 2004 , vol. 47, # 23 p. 5729 - 5742
