2-(4-甲氧基苄氧基)噻吩合成路线 （共 23 条）
反应条件
titanium tetrachloride in dichloromethane T=22°C; 3.5 h;
参考文献
Katritzky, Alan R.; Suzuki, Kazuyuki; Singh, Sandeep K.
Croatica Chemica Acta, 2004 , vol. 77, # 1-2 p. 175 - 178
反应条件
1: 1-bromo-4-methoxy-benzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.25 h; 2: thiophene-2-carbaldehyde in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
Hamad, Abdel-Sattar S.
Phosphorus, Sulfur and Silicon and Related Elements, 2001 , vol. 170, p. 65 - 74
反应条件
iron silicate T=25°C; Friedel-Crafts acylation;
参考文献
Borate, Hanumant B.; Gaikwad, Abaji G.; Maujan, Suleman R.; Sawargave, Sangmeshwer P.; Kalal, Kamalakar M.
Tetrahedron Letters, 2007 , vol. 48, # 28 p. 4869 - 4872
反应条件
3,3-dimethyl-butan-2-one; [Ru(CO)3Cl2]2; K3PO4*3H2O; [(t-Bu)3PH]BF4 in water; toluene T=100°C; 24 h; Inert atmosphere;
参考文献
Li, Hong; Xu, Yuan; Shi, Erbo; Wei, Wei; Suo, Xiangqiang; Wan, Xiaobing
Chemical Communications, 2011 , vol. 47, # 27 p. 7880 - 7882
反应条件
Cu(I) 3-methylsalicylate in N,N-dimethyl-formamide 1 h; Microwave irradiationHeatingInert atmosphereSealed tube;
参考文献
Zhang, Zhihui; Lindale, Matthew G.; Liebeskind, Lanny S.
Journal of the American Chemical Society, 2011 , vol. 133, # 16 p. 6403 - 6410
反应条件
in tetrahydrofuran T=-15 - 20°C; 1.5 h;
参考文献
Lee, Jae In
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 3 p. 749 - 752
反应条件
trifluoromethanesulfonic acid 2-pyridinyl ester; trifluoroacetic acid 4 h; Heating;
参考文献
Keumi, Takashi; Yoshimura, Kiichiro; Shimada, Masakazu; Kitajima, Hidehiko
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, p. 455 - 460
反应条件
1: 72 percent / Et3N / tetrahydrofuran / Heating 2: 78 percent / TiCl4 / CH2Cl2 / 3.5 h / 22 °C View Scheme
参考文献
Jeon, Kyu Ok; Jun, Jung Ho; Yu, Ji Sook; Lee, Chang Kiu
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 5 p. 763 - 771
反应条件
in tetrahydrofuran T=0 - 20°C; 0.5 h; Yield given;
参考文献
Lee, Na Ra; Lee, Jae In
Synthetic Communications, 1999 , vol. 29, # 8 p. 1249 - 1255
反应条件
1: tin (IV)-chloride; benzene 2: aq.-ethanolic NaOH-solution 3: aq.-ethanolic KOH-solution View Scheme
参考文献
Royer; Demerseman
Bulletin de la Societe Chimique de France, 1959 , p. 1682,1685
