(4-溴苯基)-2-噻吩-甲酮合成路线 （共 6 条）
反应条件
pyridinium chlorochromate in dichloromethane
T=20°C; 0.5 h;
参考文献
Mahalingam; Wan, Yiqian; Murugaiah; Wallinder, Charlotta; Wu, Xiongyu; Plouffe, Bianca; Botros, Milad; Nyberg, Fred; Hallberg, Anders; Gallo-Payet, Nicole; Alterman, Mathias
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 12 p. 4570 - 4590
反应条件
in tetrahydrofuran
T=0°C; 1.1666 h;
参考文献
Wyeth
Patent: US2007/66675 A1, 2007 ;
Location in patent: Page/Page column 16 ;
反应条件
tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate in methoxybenzene
T=100°C; Suzuki carbonylative coupling; P=760.051 Torr; 20 h; chemoselective reaction;
参考文献
Li, Hongling; Yang, Min; Qi, Yanxing; Xue, Jijun
European Journal of Organic Chemistry, 2011 , # 14 p. 2662 - 2667
反应条件
aluminium trichloride in carbon disulfide
1.) RT, 13.5 h, 2.) reflux, 3 h;
参考文献
McKean, D. R.; Parrinello, G.; Renaldo, A. F.; Stille, J. K.
Journal of Organic Chemistry, 1987 , vol. 52, # 3 p. 422 - 424
反应条件
[2,2']bipyridinyl; (1S)-10-camphorsulfonic acid; water; palladium diacetate
T=110°C; 36 h;
参考文献
Jiang, Tao-Shan; Wang, Guan-Wu
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 369 - 373
反应条件
1: thionyl chloride
2: 77 percent / AlCl3 / Heating
View Scheme
参考文献
Jeon, Kyu Ok; Jun, Jung Ho; Yu, Ji Sook; Lee, Chang Kiu
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 5 p. 763 - 771
