N-(乙酰基氯)甘氨酸乙酯合成路线 （共 6 条）
反应条件
1: glycine ethyl ester hydrochloric acid With N-ethyl-N,N-diisopropylamine in toluene T=-10°C; Inert atmosphere; 2: chloroacetyl chloride in toluene T=0 - 20°C; 2.33333 h; Inert atmosphere;
参考文献
Pautus, Stephane; Sehr, Peter; Lewis, Joe; Fortune, Antoine; Wolkerstorfer, Andrea; Szolar, Oliver; Guilligay, Delphine; Lunardi, Thomas; Decout, Jean-Luc; Cusack, Stephen
Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8915 - 8930
反应条件
in ethyl acetate 7.5 h; Heating;
参考文献
Goodson, John J.; Wharton, Clifford J.; Wrigglesworth, Roger
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2721 - 2727
反应条件
hydrogenchloride; diethyl ether
参考文献
Looker,J.H.; Carpenter,J.W.
Canadian Journal of Chemistry, 1967 , vol. 45, p. 1727 - 1734
反应条件
1: NaNO2, aq. Na2CO3 2: phenoxy-acetyl chloride / CH2Cl2 View Scheme
参考文献
Looker,J.H.; Carpenter,J.W.
Canadian Journal of Chemistry, 1967 , vol. 45, p. 1727 - 1734
参考文献
Diels; Heintzel
Chemische Berichte, 1905 , vol. 38, p. 304
参考文献
Diels; Heintzel
Chemische Berichte, 1905 , vol. 38, p. 304
