4-(二甲氨基)邻羟苄基合成路线 （共 16 条）
反应条件
1: 56 percent / KOH / ethanol / 7 h / Heating 2: 86 percent / CH3ONa / ethanol / 0.33 h / Heating 3: 81 percent / active carbon, FeCl3*6H2O, hydrazine / benzene; methanol / 7 h / Heating 4: 84 percent 5: 46 percent / AcONa / acetic anhydride / Heating View Scheme
参考文献
Akiyama, Shuzo; Akimoto, Hiroyuki; Nakatsuji, Shin'ichi; Nakashima, Kenichiro
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 8 p. 2192 - 2196
反应条件
piperidine; acetic acid in ethanol Knoevenagel Condensation; 3 h; Reflux;
参考文献
Draoui, Nihed; Schicke, Olivier; Fernandes, Antony; Drozak, Xavier; Nahra, Fady; Dumont, Amelie; Douxfils, Jonathan; Hermans, Emmanuel; Dogne, Jean-Michel; Corbau, Romu; Marchand, Arnaud; Chaltin, Patrick; Sonveaux, Pierre; Feron, Olivier; Riant, Olivier
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 7107 - 7117
反应条件
1: 40 percent / piperidine / ethanol / 4 h / Heating 2: 98 percent / aq. NaOH / methanol / 0.08 h / Heating View Scheme
参考文献
Hori, Yuichiro; Norinobu, Tomoya; Sato, Motoki; Arita, Kyohei; Shirakawa, Masahiro; Kikuchi, Kazuya
Journal of the American Chemical Society, 2013 , vol. 135, # 33 p. 12360 - 12365
反应条件
piperidine in ethanol
6 h; Heating / reflux;
参考文献
Barrio, Jorge R.; Petric, Andre J.; Satyamurthy, Nagichettiar; Kepe, Vladimir; Small, Gary W.
Patent: US2007/53831 A1, 2007 ;
Location in patent: Page/Page column 11 ;
反应条件
1: 56 percent / KOH / ethanol / 7 h / Heating
2: 86 percent / CH3ONa / ethanol / 0.33 h / Heating
View Scheme
参考文献
Akiyama, Shuzo; Akimoto, Hiroyuki; Nakatsuji, Shin'ichi; Nakashima, Kenichiro
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 8 p. 2192 - 2196
反应条件
1: 56 percent / KOH / ethanol / 7 h / Heating
2: 86 percent / CH3ONa / ethanol / 0.33 h / Heating
3: 81 percent / active carbon, FeCl3*6H2O, hydrazine / benzene; methanol / 7 h / Heating
View Scheme
参考文献
Akiyama, Shuzo; Akimoto, Hiroyuki; Nakatsuji, Shin'ichi; Nakashima, Kenichiro
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 8 p. 2192 - 2196
