1,3-二甲基-5-硝基尿嘧啶水合物合成路线 （共 28 条）
反应条件
sodium hydroxide; dimethyl sulfate
参考文献
Bredereck; Edenhofer
Chemische Berichte, 1955 , vol. 88, p. 1306,1309
参考文献
Pruesse
Justus Liebigs Annalen der Chemie, 1925 , vol. 441, p. 209
参考文献
Behrend; Lehmann
Justus Liebigs Annalen der Chemie, 1889 , vol. 253, p. 77,84
参考文献
Hirota, Kosaku; Kitade, Yukio; Sajiki, Hironao; Maki, Yoshifumi
Tetrahedron Letters, 1986 , vol. 27, # 28 p. 3263 - 3266
反应条件
Bacillus subtilis nitroreductase Nfr-A1; ammonium hydrogen carbonate T=37°C; pH=8.4; 3 h; Inert atmosphereEnzymatic reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 76, p. 1 - 8
反应条件
potassium hydroxide in ethanol 3 h; Heating;
参考文献
Hirota, Kosaku; Kitade, Yukio; Senda, Shigeo
Heterocycles, 1980 , vol. 14, # 4 p. 407 - 410
反应条件
1: 70 percent / iron; hydrochloric acid / tetrahydrofuran; H2O / 0.5 h / Heating 2: Heating 3: nitric acid; sulfuric acid / 1 h / Heating 4: 75 percent / acetic acid; iron / 0.5 h / Heating View Scheme
参考文献
Zajac, Matthew A.; Zakrzewski, Anthony G.; Kowal, Mark G.; Narayan, Saraswathi
Synthetic Communications, 2003 , vol. 33, # 19 p. 3291 - 3297
反应条件
1: Raney nickel; ethanol / Hydrogenation View Scheme
参考文献
Pfleiderer; Liedek
Justus Liebigs Annalen der Chemie, 1958 , vol. 612, p. 184
反应条件
1: 70 percent / iron; hydrochloric acid / tetrahydrofuran; H2O / 0.5 h / Heating 2: Heating 3: nitric acid; sulfuric acid / 1 h / Heating 4: 75 percent / acetic acid; iron / 0.5 h / Heating 5: 95 percent / sodium hydride / dimethylsulfoxide / 0.75 h View Scheme
参考文献
Zajac, Matthew A.; Zakrzewski, Anthony G.; Kowal, Mark G.; Narayan, Saraswathi
Synthetic Communications, 2003 , vol. 33, # 19 p. 3291 - 3297
反应条件
Bacillus subtilis nitroreductase Nfr-A1; ammonium hydrogen carbonate
T=37°C; pH=8.4; 3 h; Inert atmosphereEnzymatic reaction;
参考文献
Cortial, Sylvie; Chaignon, Philippe; Sergent, Didier; Dezard, Sophie; Ouazzani, Jamal
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 76, p. 1 - 8
