1-((吡啶-2-基)甲基)-4-哌啶酮合成路线 （共 12 条）
反应条件
sodium carbonate in acetonitrile T=20 - 70°C;
参考文献
Faul, Margaret M.; Kobierski, Michael E.; Kopach, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5739 - 5741
反应条件
sodium carbonate in acetonitrile T=23°C;
参考文献
Faul, Margaret M.; Kobierski, Michael E.; Kopach, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5739 - 5741
反应条件
sodium carbonate in acetonitrile T=23°C;
参考文献
Faul, Margaret M.; Kobierski, Michael E.; Kopach, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5739 - 5741
反应条件
sodium carbonate in acetonitrile T=23°C;
参考文献
Faul, Margaret M.; Kobierski, Michael E.; Kopach, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5739 - 5741
反应条件
sodium carbonate in acetonitrile T=70 - 72°C; 5 h; Inert atmosphere;
参考文献
Boini, Sathish; Moder, Kenneth P.; Vaid, Radhe K.; Kopach, Micheal; Kobierski
Organic Process Research and Development, 2006 , vol. 10, # 6 p. 1205 - 1211
反应条件
hydrogenchloride; ethanol; sodium 1.) toluene; Yield given. Multistep reaction;
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
反应条件
1: ethanol / Heating 2: t-BuOK / tetrahydrofuran 3: LiOH / H2O / Heating View Scheme
参考文献
Hosken, Gladys D.; Hancock, Robert D.
Journal of the Chemical Society, Chemical Communications, 1994 , # 11 p. 1363 - 1364
反应条件
1: Na2CO3 / acetonitrile / Heating 2: acetic acid; HCl / H2O / 18 h / 60 °C View Scheme
参考文献
Faul, Margaret M.; Kobierski, Michael E.; Kopach, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5739 - 5741
反应条件
1: Na2CO3 / acetonitrile / Heating 2: acetic acid; HCl / H2O / 18 h / 60 °C View Scheme
参考文献
Faul, Margaret M.; Kobierski, Michael E.; Kopach, Michael E.
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5739 - 5741
反应条件
1.1: 85 percent / NaBH(OAc)3 / acetic acid / 3 h / 20 °C 2.1: 90 percent / DDQ / tetrahydrofuran / 1 h / 0 - 5 °C 3.1: HCl gas / acetonitrile / 0.5 h / 0 - 20 °C 3.2: acetonitrile / 2 h / -10 - 0 °C 3.3: 86.5 percent / acetonitrile / 1 h / -10 - 0 °C 4.1: 75 percent / t-BuOK / tetrahydrofuran / -5 - 45 °C View Scheme
参考文献
Faul, Margaret M.; Grutsch, John L.; Kobierski, Michael E.; Kopach, Michael E.; Krumrich, Christine A.; Staszak, Michael A.; Udodong, Uko; Vicenzi, Jeffrey T.; Sullivan, Kevin A.
Tetrahedron, 2003 , vol. 59, # 36 p. 7215 - 7229
