2,2,3-三甲基-3-丁烯酸合成路线 （共 22 条）
反应条件
1: 88 percent / tetrahydrofuran
2: 78 percent / P2O5 / benzene
3: 84 percent / LiOH, H2O / ethanol / Ambient temperature
View Scheme
参考文献
Kim, Hyoung Rae; Shin, Seung Il; Park, Hyun Ju; Jeon, Dong Ju; Ryu, Eung K.
Synlett, 1998 , # 7 p. 789 - 791
反应条件
1: 78 percent / P2O5 / benzene
2: 84 percent / LiOH, H2O / ethanol / Ambient temperature
View Scheme
参考文献
Kim, Hyoung Rae; Shin, Seung Il; Park, Hyun Ju; Jeon, Dong Ju; Ryu, Eung K.
Synlett, 1998 , # 7 p. 789 - 791
反应条件
1: NaNH2 / liquid ammonia
2: KOH / ethane-1,2-diol / 65 h / 140 °C
View Scheme
参考文献
Fleury,J.-P.; Bader,A.
Bulletin de la Societe Chimique de France, 1965 , p. 951 - 957
反应条件
1: NaNH2 / liquid ammonia
2: NaNH2 / liquid ammonia
3: KOH / ethane-1,2-diol / 65 h / 140 °C
View Scheme
参考文献
Fleury,J.-P.; Bader,A.
Bulletin de la Societe Chimique de France, 1965 , p. 951 - 957
反应条件
1: NaNH2 / liquid ammonia
2: NaNH2 / liquid ammonia
3: KOH / ethane-1,2-diol / 65 h / 140 °C
View Scheme
参考文献
Fleury,J.-P.; Bader,A.
Bulletin de la Societe Chimique de France, 1965 , p. 951 - 957
反应条件
potassium hydroxide
1.)THF,RT, 2.)MeOH/H2O; Multistep reaction;
参考文献
Karpf, Martin
Tetrahedron Letters, 1982 , vol. 23, # 47 p. 4923 - 4926
反应条件
copper(l) iodide; dimethylsulfide
1) THF, -30 deg C, 30 min; 2) THF, -30 deg C, 1 h, 0 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Kawashima, Masatoshi; Sato, Toshio; Fujisawa, Tamotsu
Tetrahedron, 1989 , vol. 45, # 2 p. 403 - 412
反应条件
und Erwaermen des Reaktionsprodukts mit Wasser;
参考文献
Malachowski; Jurkiewicz
Roczniki Chemii, 1950 , vol. 24, p. 88,107
Chem.Abstr., 1954 , p. 3914
反应条件
1: platinum; acetic acid / Hydrogenation
2: phosphorus (III)-chloride
3: water; ammonia
View Scheme
参考文献
Malachowski; Jurkiewicz
Roczniki Chemii, 1950 , vol. 24, p. 88,107
Chem.Abstr., 1954 , p. 3914
反应条件
thionyl chloride
1 h; Heating;
参考文献
Karpf, Martin
Helvetica Chimica Acta, 1984 , vol. 67, # 1 p. 73 - 85
