1-Boc-4-[(N-甲氧基-N-甲基氨基甲酰基)甲基]哌啶合成路线 （共 3 条）
反应条件
in tetrahydrofuran; diethyl ether T=-78 - 0°C; 1.83333 h;
参考文献
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1386920 A1, 2004 ;
Location in patent: Page 50 ;
反应条件
bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
0.5 h;
参考文献
Reck, Folkert; Zhou, Fei; Eyermann, Charles J.; Kern, Gunther; Carcanague, Dan; Ioannidis, Georgine; Illingworth, Ruth; Poon, Grace; Gravestock, Michael B.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 20 p. 4868 - 4881
反应条件
O,N-dimethyl-hydroxylamine hydrochloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in chloroform
参考文献
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1386920 A1, 2004 ;
Location in patent: Page 50 ;
