2-(3-硝基苯磺酰基)乙醇合成路线 （共 5 条）
反应条件
sulfuric acid; potassium nitrate T=90°C; 2 h;
参考文献
Boehringer Ingelheim Pharma GmbH and Co. KG
Patent: EP1953163 A1, 2008 ;
Location in patent: Page/Page column 17 ;
EP 1953163 A1
反应条件
MOA; dihydrogen peroxide in acetone Yield given;
参考文献
Samukov, V. V.; Sabirov, A. N.; Troshkov, M. L.
J. Gen. Chem. USSR (Engl. Transl.), 1988 , vol. 58, # 6 p. 1432 - 1439,1277 - 1283
参考文献
Limpricht
Justus Liebigs Annalen der Chemie, 1897 , vol. 294, p. 248
反应条件
hydrogen; palladium 10 on activated carbon in tetrahydrofuran; ethanol
参考文献
Boehringer Ingelheim Pharma GmbH and Co. KG
Patent: EP1953163 A1, 2008 ;
Location in patent: Page/Page column 16-17 ;
EP 1953163 A1
反应条件
1: 3-carboxybenzenesulfonyl chloride With phosphorus pentachloride
T=20 - 70°C; 2 h;
2: 2-(3-nitro-benzenesulfonyl)-ethanol in acetonitrile
36 h; Heating / reflux;
参考文献
Shin, Jai Moo; Sachs, George; Cho, Young-Moon; Garst, Michael
Molecules, 2009 , vol. 14, # 12 p. 5247 - 5280
