2-环戊基-5-羟基-6,7-二甲基-2,3-二氢-1H-茚-1-酮合成路线 （共 5 条）
反应条件
boron tribromide in dichloromethane
T=20°C; 4 h;
参考文献
Galici, Ruggero; Jones, Carrie K.; Hemstapat, Kamondanai; Nong, Yi; Echemendia, Nicholas G.; Williams, Lilly C.; De Paulis, Tomas; Conn, P. Jeffrey
Journal of Pharmacology and Experimental Therapeutics, 2006 , vol. 318, # 1 p. 173 - 185
反应条件
1: 98 percent / aluminium trichloride / CH2Cl2 / 16 h / 20 °C
2: 84 percent / dimethylamine hydrochloride / acetic acid / 18 h / 95 °C
3: 82 percent / H2SO4 / 3 h / 20 °C
4: 51 percent / boron tribromide / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Galici, Ruggero; Jones, Carrie K.; Hemstapat, Kamondanai; Nong, Yi; Echemendia, Nicholas G.; Williams, Lilly C.; De Paulis, Tomas; Conn, P. Jeffrey
Journal of Pharmacology and Experimental Therapeutics, 2006 , vol. 318, # 1 p. 173 - 185
反应条件
1: 84 percent / dimethylamine hydrochloride / acetic acid / 18 h / 95 °C
2: 82 percent / H2SO4 / 3 h / 20 °C
3: 51 percent / boron tribromide / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Galici, Ruggero; Jones, Carrie K.; Hemstapat, Kamondanai; Nong, Yi; Echemendia, Nicholas G.; Williams, Lilly C.; De Paulis, Tomas; Conn, P. Jeffrey
Journal of Pharmacology and Experimental Therapeutics, 2006 , vol. 318, # 1 p. 173 - 185
反应条件
1: 82 percent / H2SO4 / 3 h / 20 °C
2: 51 percent / boron tribromide / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Galici, Ruggero; Jones, Carrie K.; Hemstapat, Kamondanai; Nong, Yi; Echemendia, Nicholas G.; Williams, Lilly C.; De Paulis, Tomas; Conn, P. Jeffrey
Journal of Pharmacology and Experimental Therapeutics, 2006 , vol. 318, # 1 p. 173 - 185
反应条件
1: SoCl2 / toluene
2: 98 percent / aluminium trichloride / CH2Cl2 / 16 h / 20 °C
3: 84 percent / dimethylamine hydrochloride / acetic acid / 18 h / 95 °C
4: 82 percent / H2SO4 / 3 h / 20 °C
5: 51 percent / boron tribromide / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Galici, Ruggero; Jones, Carrie K.; Hemstapat, Kamondanai; Nong, Yi; Echemendia, Nicholas G.; Williams, Lilly C.; De Paulis, Tomas; Conn, P. Jeffrey
Journal of Pharmacology and Experimental Therapeutics, 2006 , vol. 318, # 1 p. 173 - 185
