boron tribromide in dichloromethane T=20°C; 7 h;

β-glucosidase in water T=37°C; 20 h;

1.1: LDA / tetrahydrofuran; cyclohexane / 0.33 h / -78 °C 1.2: 32 percent / tetrahydrofuran; cyclohexane / -78 - 20 °C 2.1: 85 percent / BBr3 / CH2Cl2 / 7 h / 20 °C View Scheme