2,4-二溴噻唑合成路线

Athmani, Salah; Bruce, Andrew; Iddon, Brian
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 2 p. 215 - 219

110-91-8吗啉+

4175-77-32,4-二溴噻唑

1017781-60-0

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2008/70507 A2, 2008 ;
Location in patent: Page/Page column 179 ;

4175-77-32,4-二溴噻唑+

68-12-2N,N-二甲基甲酰胺

139669-95-72,4-二溴噻唑-5-甲醛

参考文献

PHENEX PHARMACEUTICALS AG; GEGE, Christian; STEENECK, Christoph; KINZEL, Olaf; KLEYMANN, Gerald; HOFFMANN, Thomas
Patent: WO2013/178362 A1, 2013 ;
Location in patent: Page/Page column 156 ;

4175-77-32,4-二溴噻唑

108306-53-2

参考文献

VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/87698 A2, 2004 ;
Location in patent: Page 37; 50 ;
WO 2004/087698 A2

75-77-4三甲基氯硅烷+

4175-77-32,4-二溴噻唑

108306-53-2

参考文献

Dondoni, Alessandro; Fantin, Giancarlo; Fogagnolo, Marco; Medici, Alessandro; Pedrini, Paola
Journal of Organic Chemistry, 1988 , vol. 53, # 8 p. 1748 - 1761