2,4-二溴噻唑合成路线

参考文献

EP2455371 A1, ;

Page/Page column 24 ;

参考文献

Nicolaou; He, Yun; Roschangar, Frank; Paul King; Vourloumis, Dionisios; Li, Tianhu
Angewandte Chemie - International Edition, 1998 , vol. 37, # 1-2 p. 84 - 87

4394-85-8N-甲酰吗啉+

4175-77-32,4-二溴噻唑

167366-05-44-溴-2-醛基噻唑

参考文献

Pop, Laura; Lassalas, Pierrik; Bencze, Laszlo Csaba; Tosa, Monica Ioana; Nagy, Botond; Irimie, Florin Dan; Hoarau, Christophe
Tetrahedron Asymmetry, 2012 , vol. 23, # 6-7 p. 474 - 481

4175-77-32,4-二溴噻唑+

77-78-1硫酸二甲酯

298694-30-14-溴-2-甲基噻唑

参考文献

Russian Journal of Organic Chemistry, , vol. 46, # 11 p. 1702 - 1708

4175-77-32,4-二溴噻唑+

5188-07-8甲硫醇钠

204513-62-24-溴-2-(甲基硫代)噻唑

参考文献

Nicolaou; He, Yun; Roschangar, Frank; Paul King; Vourloumis, Dionisios; Li, Tianhu
Angewandte Chemie - International Edition, 1998 , vol. 37, # 1-2 p. 84 - 87

1765-93-14-氟苯硼酸+

4175-77-32,4-二溴噻唑

1142196-38-0

参考文献

NOVARTIS AG
Patent: WO2009/115572 A2, 2009 ;
Location in patent: Page/Page column 113 ;
WO 2009/115572 A2

4175-77-32,4-二溴噻唑+

411235-57-9环丙基硼酸

1086381-69-24-溴-2-环丙基-5-甲基噻唑

参考文献

Strotman, Neil A.; Chobanian, Harry R.; He, Jiafang; Guo, Yan; Dormer, Peter G.; Jones, Christina M.; Steves, Janelle E.
Journal of Organic Chemistry, 2010 , vol. 75, # 5 p. 1733 - 1739

110-85-0哌嗪+

4175-77-32,4-二溴噻唑

668484-59-14-溴-2-(哌嗪-1-基)噻唑

参考文献

THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; THE UNIVERSITY OF MASSACHUSETTS; MARUGAN, Juan Jose; XIAO, Jingbo; TITUS, Steven A.; SOUTHALL, Noel; ZHENG, Wei; ANDROPHY, Elliot J.; CHERRY, Jonathan
Patent: WO2011/130515 A1, 2011 ;
Location in patent: Page/Page column 24 ;

4175-77-32,4-二溴噻唑+

74-89-5甲胺

932738-66-4

参考文献

Satoh, Atsushi; Nagatomi, Yasushi; Hirata, Yukari; Ito, Satoru; Suzuki, Gentaroh; Kimura, Toshifumi; Maehara, Shunsuke; Hikichi, Hirohiko; Satow, Akio; Hata, Mikiko; Ohta, Hisashi; Kawamoto, Hiroshi
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 18 p. 5464 - 5468