1: hexane; diethyl ether / 0.5 h / Ambient temperature; addition of reagent - 15 deg C 3: triethylamine / CHCl3 / 0.5 h / Ambient temperature 4: tetrazole / acetonitrile; tetrahydrofuran / 3 h / Ambient temperature 5: t-butyl hydroperoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h 6: trimethylamine / toluene / 12 h / Ambient temperature 7: tetrabutylammonium fluoride / tetrahydrofuran / 48 h / Ambient temperature 8: sodium deoxycholate / 37 °C / phospholipaze in HEPES buffer (pH 8.0) View Scheme

1: hexane; diethyl ether / 0.5 h / Ambient temperature; addition of reagent - 15 deg C 3: triethylamine / CHCl3 / 0.5 h / Ambient temperature 4: tetrazole / acetonitrile; tetrahydrofuran / 3 h / Ambient temperature 5: t-butyl hydroperoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h 6: trimethylamine / toluene / 12 h / Ambient temperature 7: tetrabutylammonium fluoride / tetrahydrofuran / 48 h / Ambient temperature 8: sodium deoxycholate / 37 °C / phospholipaze in HEPES buffer (pH 8.0) View Scheme