2-溴-4,6-二甲基苯胺合成路线 （共 24 条）
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water
T=95°C; Suzuki-coupling reaction; 12 h;
参考文献
Joe, Dae June; Wu, Chun Ji; Bok, Taekki; Lee, Eun Jung; Lee, Choong Hoon; Han, Won-Sik; Kang, Sang Ook; Lee, Bun Yeoul
Dalton Transactions, 2006 , # 33 p. 4056 - 4062
反应条件
1: 96 percent / Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane; H2O / 12 h / 95 °C
2: 70 percent / CeCl3 / tetrahydrofuran; diethyl ether / 2 h / -78 °C
View Scheme
参考文献
Joe, Dae June; Wu, Chun Ji; Bok, Taekki; Lee, Eun Jung; Lee, Choong Hoon; Han, Won-Sik; Kang, Sang Ook; Lee, Bun Yeoul
Dalton Transactions, 2006 , # 33 p. 4056 - 4062
反应条件
1: 74 percent / Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane; H2O / 12 h / 95 °C
2: 75 percent / CeCl3 / tetrahydrofuran; diethyl ether / 2 h / -78 °C
View Scheme
参考文献
Joe, Dae June; Wu, Chun Ji; Bok, Taekki; Lee, Eun Jung; Lee, Choong Hoon; Han, Won-Sik; Kang, Sang Ook; Lee, Bun Yeoul
Dalton Transactions, 2006 , # 33 p. 4056 - 4062
反应条件
1: 60 percent / Gattermann reaction
2: 50 percent / dimethylsulfoxide / 2.5 h / 45 °C / Irradiation
3: 34percent hydrogen peroxide, glacial acetic acid / 100 °C
4: tetrabutylammonium acetate / dimethylsulfoxide / controlled-potential electrolysis, mercury pool cathode, 0.1M tetrabutylammonium tetrafluoroborate; reaction without base
View Scheme
参考文献
Novi, Marino; Garbarino, Giacomo; Petrillo, Giovanni; Dell'Erba, Carlo
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1987 , p. 623 - 632
