5,6,7,8-四氢萘-1-甲醛合成路线 （共 25 条）
反应条件
permanganate(VII) ion
参考文献
v. Braun
Chemische Berichte, 1922 , vol. 55, p. 1708
反应条件
1: 79 percent / sodium borohydride / ethanol / 1.5 h 2: 100 percent / SOCl2 / toluene / 2 h View Scheme
参考文献
Horn Jensen, Eva; Nielsen, Per Halfdan
Heterocycles, 1995 , vol. 41, # 11 p. 2441 - 2458
反应条件
manganese(IV) oxide in dichloromethane
10 h; Heating;
参考文献
Connolly, Terrence J.; Durst, Tony
Tetrahedron, 1997 , vol. 53, # 47 p. 15969 - 15982
反应条件
aluminium trichloride in chlorobenzene
T=3 - 20°C; Formylation; 4.5 h;
参考文献
Kantlehner, Willi; Vettel, Markus; Gissel, Alexander; Haug, Erwin; Ziegler, Georg; Ciesielski, Michael; Scherr, Oliver; Haas, Richard
Advanced Synthesis and Catalysis, 2000 , vol. 342, # 3 p. 297 - 310
反应条件
tert.-butyl lithium in tetrahydrofuran; diethyl ether; pentane
T=-78 - 20°C; Cyclization; 3-steps cascade;
参考文献
Bailey, William F.; Longstaff, Sarah C.
Tetrahedron Letters, 1999 , vol. 40, # 38 p. 6899 - 6901
反应条件
1: With L-proline in acetonitrile
T=32°C; 2 h;
2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in dichloromethane; acetonitrile
T=32°C; 2 h;
参考文献
Hong, Bor-Cherng; Tseng, Hsing-Chang; Chen, Shang-Hung
Tetrahedron, 2007 , vol. 63, # 13 p. 2840 - 2850
反应条件
1: 83 percent / DIBAL-H / CH2Cl2; hexane / 2 h / 0 °C
2: 63 percent / MnO2 / CH2Cl2 / 2 h / 30 °C
3: t-Bu3P / L-proline / acetonitrile / 66 h / 0 °C
4: DDQ / acetonitrile; CH2Cl2 / 2 h / 30 °C
View Scheme
参考文献
Hong, Bor-Cherng; Tseng, Hsing-Chang; Chen, Shang-Hung
Tetrahedron, 2007 , vol. 63, # 13 p. 2840 - 2850
反应条件
1: 63 percent / MnO2 / CH2Cl2 / 2 h / 30 °C
2: t-Bu3P / L-proline / acetonitrile / 66 h / 0 °C
3: DDQ / acetonitrile; CH2Cl2 / 2 h / 30 °C
View Scheme
参考文献
Hong, Bor-Cherng; Tseng, Hsing-Chang; Chen, Shang-Hung
Tetrahedron, 2007 , vol. 63, # 13 p. 2840 - 2850
反应条件
1: t-Bu3P / L-proline / acetonitrile / 66 h / 0 °C
2: DDQ / acetonitrile; CH2Cl2 / 2 h / 30 °C
View Scheme
参考文献
Hong, Bor-Cherng; Tseng, Hsing-Chang; Chen, Shang-Hung
Tetrahedron, 2007 , vol. 63, # 13 p. 2840 - 2850
反应条件
SbF5; epoxysulfonyl fluoride
T=0°C; P=760 Torr; 1 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tanaka, Mutsuo; Iyoda, Jun; Souma, Yoshie
Journal of Organic Chemistry, 1992 , vol. 57, # 9 p. 2677 - 2680
