2-Boc-硫代-4,6-二甲基嘧啶合成路线 （共 50 条）
反应条件
triethylamine in 1,4-dioxane; water
6 h; Ambient temperature;
参考文献
Tanaka, Ken-Ichi; Yoshifuji, Shigeyuki; Nitta, Yoshihiro
Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 8 p. 3125 - 3129
反应条件
in pyridine; methanol; chloroform; water
参考文献
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
Patent: US4518802 A1, 1985 ;
反应条件
triethylamine in 1,4-dioxane; water
T=20°C; 12 h;
参考文献
Obase; Takai; Teranishi; Nakamizo
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 565 - 573
反应条件
1: 94 percent / triethylamine / H2O; dioxane / 6 h / Ambient temperature
2: 70 percent / ruthenium dioxide hydrate, 10percent aqueous NaIO4 / ethyl acetate / 0.5 h / Ambient temperature
View Scheme
参考文献
Tanaka, Ken-Ichi; Yoshifuji, Shigeyuki; Nitta, Yoshihiro
Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 8 p. 3125 - 3129
反应条件
1: 49.0 g / Et3N / dioxane; H2O / 21 h / Ambient temperature
2: NaBH4 / ethanol / 1) 5 deg C, 15 min. 2) room temp. 70 min.
View Scheme
参考文献
Saito, Kunio; Saijo, Shigeyoshi; Kotera, Keishi; Date, Tadamasa
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 4 p. 1342 - 1350
反应条件
triethylamine in 1,4-dioxane; water
6 h; Ambient temperature;
参考文献
Tanaka, Ken-Ichi; Yoshifuji, Shigeyuki; Nitta, Yoshihiro
Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 8 p. 3125 - 3129
反应条件
triethanolamine in diethyl ether; ethanol; water; acetonitrile
参考文献
Takeda Chemical Industries, Ltd.
Patent: US4358440 A1, 1982 ;
反应条件
triethylamine in 1,4-dioxane; water
6 h; Ambient temperature;
参考文献
Tanaka, Ken-Ichi; Yoshifuji, Shigeyuki; Nitta, Yoshihiro
Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 8 p. 3125 - 3129
反应条件
in water; N,N-dimethyl-formamide
T=50°C; 2 h;
参考文献
Ojima, Iwao; Kogure, Tetsuo; Yoda, Noriko
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4728 - 4739
反应条件
triethylamine in 1,4-dioxane; water
6 h; Ambient temperature;
参考文献
Tanaka, Ken-Ichi; Yoshifuji, Shigeyuki; Nitta, Yoshihiro
Chemical & Pharmaceutical Bulletin, 1988 , vol. 36, # 8 p. 3125 - 3129
