4-溴苯乙酸甲酯合成路线

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GmbH; BOEHRINGER INGELHEIM PHARMA GmbH and CO KG
Patent: WO2005/118575 A1, 2005 ;
Location in patent: Page/Page column 81 ;
WO 2005/118575 A1

67-56-1甲醇+

99-90-14-溴苯乙酮+

149-73-5原甲酸三甲酯

41841-16-14-溴苯乙酸甲酯+

81585-75-3

参考文献

Higgins, Stanley D.; Thomas, Barry C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 235 - 242

67-56-1甲醇+

1360789-06-5

41841-16-14-溴苯乙酸甲酯

参考文献

Hutchby, Marc; Houlden, Chris E.; Haddow, Mairi F.; Tyler, Simon N. G.; Lloyd-Jones, Guy C.; Booker-Milburn, Kevin I.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 2 p. 548 - 551

16532-79-9对溴苯乙腈+

201230-82-2+

124-41-4甲醇钠

52787-14-14-甲酸甲酯苯乙酸甲酯+

41841-16-14-溴苯乙酸甲酯+

76469-88-0对氰基甲基苯甲酸甲酯

参考文献

Dneprovskii, A. S.; Tuchkin, A. I.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 3.2 p. 435 - 441
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 3 p. 404 - 410

参考文献

Laila, Abdulhameed A. R.
Gazzetta Chimica Italiana, 1989 , vol. 119, # 8 p. 453 - 456

41841-16-14-溴苯乙酸甲酯

52798-01-3P-氰基苯乙酸甲酯

参考文献

BAYER PHARMA AKTIENGESELLSCHAFT
Patent: US2012/172448 A1, 2012 ;
Location in patent: Page/Page column 28 ;

557-21-1氰化锌+

41841-16-14-溴苯乙酸甲酯

52798-01-3P-氰基苯乙酸甲酯

参考文献

Pfizer Products Inc.
Patent: EP1229034 A1, 2002 ;
Location in patent: Page 120 ;
EP 1229034 B1

41841-16-14-溴苯乙酸甲酯+

544-92-3氰化亚铜

52798-01-3P-氰基苯乙酸甲酯

参考文献

Le Bourdonnec, Bertrand; Ajello, Christopher W.; Seida, Pamela R.; Susnow, Roberta G.; Cassel, Joel A.; Belanger, Serge; Stabley, Gabriel J.; DeHaven, Robert N.; DeHaven-Hudkins, Diane L.; Dolle, Roland E.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2647 - 2652

41841-16-14-溴苯乙酸甲酯

4654-39-14-溴苯乙醇

参考文献

Piscitelli, Francesco; Ligresti, Alessia; La Regina, Giuseppe; Coluccia, Antonio; Morera, Ludovica; Allara, Marco; Novellino, Ettore; Di Marzo, Vincenzo; Silvestri, Romano
Journal of Medicinal Chemistry, 2012 , vol. 55, # 11 p. 5627 - 5631

41841-16-14-溴苯乙酸甲酯+

73183-34-3联硼酸频那醇酯

454185-98-9

参考文献

SANKYO COMPANY, LIMITED
Patent: WO2006/109633 A1, 2006 ;
Location in patent: Page/Page column 155-156 ;