(S)-2-甲氧酰胺基-3-苯丙酸甲酯合成路线 （共 3 条）
反应条件
1: 76 percent / BuLi, TMSCl / tetrahydrofuran / -78 °C 2: 89 percent / Al(i-PrO)3 / propan-2-ol / 50 °C 3: 1.) aq. NaOH / 1.) toluene, 2.) EtOH, 60 deg C 4: 98 percent / aq. NaOH / ethanol / 80 °C View Scheme
参考文献
Goehring, Wolfgang; Gokhale, Surendra; Hilpert, Hans; Roessler, Felix; Schlageter, Markus; Vogt, Peter
Chimia, 1996 , vol. 50, # 11 p. 532 - 537
反应条件
1: 76 percent / BuLi, TMSCl / tetrahydrofuran / -78 °C 2: 89 percent / Al(i-PrO)3 / propan-2-ol / 50 °C 3: 1.) aq. NaOH / 1.) toluene, 2.) EtOH, 60 deg C 4: 98 percent / aq. NaOH / ethanol / 80 °C 6: H2 / Pd/C View Scheme
参考文献
Goehring, Wolfgang; Gokhale, Surendra; Hilpert, Hans; Roessler, Felix; Schlageter, Markus; Vogt, Peter
Chimia, 1996 , vol. 50, # 11 p. 532 - 537
反应条件
1: 76 percent / BuLi, TMSCl / tetrahydrofuran / -78 °C
2: 89 percent / Al(i-PrO)3 / propan-2-ol / 50 °C
3: 1.) aq. NaOH / 1.) toluene, 2.) EtOH, 60 deg C
4: 98 percent / aq. NaOH / ethanol / 80 °C
View Scheme
参考文献
Goehring, Wolfgang; Gokhale, Surendra; Hilpert, Hans; Roessler, Felix; Schlageter, Markus; Vogt, Peter
Chimia, 1996 , vol. 50, # 11 p. 532 - 537
