(S)-(+)-1-甲基-3-苯基丙胺合成路线 （共 50 条）
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 1 h; Enzymatic reaction; optical yield given as percent eediastereoselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized Properase 1600L in 3-methyl pentan-3-ol T=21°C; 0.666667 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized alkaline protease in 3-methyl pentan-3-ol T=21°C; 0.166667 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
immobilized alkaline protease in 3-methyl pentan-3-ol T=21°C; 3 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Bottalla, Anne-Lise; Queyroy, Severine; Azzi-Schue, Nadia; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Tetrahedron Asymmetry, 2009 , vol. 20, # 24 p. 2823 - 2834
反应条件
hydrogen; palladium dihydroxide Title compound not separated from byproducts;
参考文献
Ukaji, Yutaka; Watai, Toshiyuki; Sumi, Takashi; Fujisawa, Tamotsu
Chemistry Letters, 1991 , # 9 p. 1555 - 1558
反应条件
Candida antarctica lipase B T=28°C; 4 h;
参考文献
Gonzalez-Sabin, Javier; Gotor, Vicente; Rebolledo, Francisca
Tetrahedron Asymmetry, 2002 , vol. 13, # 12 p. 1315 - 1320
反应条件
10 palladium on activated carbon; ammonium formate in ethanol 0.5 h; Reflux; optical yield given as percent ee;
参考文献
Reznichenko, Alexander L.; Nguyen, Hiep N.; Hultzsch, Kai C.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 47 p. 8984 - 8987
反应条件
1: hydrogen / tetrahydrofuran; methanol / 12 h / 24 °C / 7500.75 Torr 2: hydrogen; palladium(II) oxide hydrate / tetrahydrofuran; methanol / 48 h / 50 °C / 15001.5 Torr View Scheme
参考文献
Nugent, Thomas C.; Negru, Daniela E.; El-Shazly, Mohamed; Hu, Dan; Sadiq, Abdul; Bibi, Ahtaram; Umar, M. Naveed
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 2085 - 2092
反应条件
Candida antarctica lipase B Title compound not separated from byproducts;
参考文献
Escoubet, Stephanie; Gastaldi, Stephane; Vanthuyne, Nicolas; Gil, Gerard; Siri, Didier; Bertrand, Michele P.
Journal of Organic Chemistry, 2006 , vol. 71, # 19 p. 7288 - 7292
反应条件
2,2,2-trifluoroethyl mercaptan in toluene T=22 - 24°C; Photolysis;
参考文献
El Blidi, Lahssen; Nechab, Malek; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2901 - 2903
