1-苯基-2-丙炔-1-醇合成路线 （共 176 条）
反应条件
in tetrahydrofuran T=20°C; Grignard reaction; 1 h;
参考文献
Matsuya, Yuji; Koiwai, Azusa; Minato, Daishiro; Sugimoto, Kenji; Toyooka, Naoki
Tetrahedron Letters, 2012 , vol. 53, # 44 p. 5955 - 5957,3
反应条件
sodium hydroxide; ethene; tetrabutylammomium bromide in toluene 2 h; Ambient temperature;
参考文献
Dehmlow, Eckehard V.; Shamout, Abdul Rahman
Liebigs Annalen der Chemie, 1982 , # 9 p. 1750 - 1752
反应条件
potassium carbonate in methanol T=20°C; 1 h; Inert atmosphere;
参考文献
Wang, Ya-Hui; Liu, Heng; Zhu, Li-Li; Li, Xiao-Xiao; Chen, Zili
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 5 p. 707 - 712
反应条件
PhONn-Bu4 in tetrahydrofuran T=-45°C; 6 h;
参考文献
Kitazawa, Takayuki; Minowa, Tomofumi; Mukaiyama, Teruaki
Chemistry Letters, 2006 , vol. 35, # 9 p. 1002 - 1003
反应条件
1.1: n-butyllithium / tetrahydrofuran / 1.5 h / -70 °C / Inert atmosphere 1.2: 1.5 h / -70 - 20 °C / Inert atmosphere 1.3: 0 °C 2.1: methanol; potassium carbonate / 12 h / 20 °C / Inert atmosphere View Scheme
参考文献
Blanchard, Christiane; Vaultier, Michel; Mortier, Jacques
Tetrahedron Letters, 1997 , vol. 38, # 51 p. 8863 - 8866
反应条件
in tetrahydrofuran T=-65 - 20°C; 1.5 h;
参考文献
Liu, Jin-Jun; Konzelmann, Fred; Luk, Kin-Chun
Tetrahedron Letters, 2003 , vol. 44, # 20 p. 3901 - 3904
反应条件
diethyl ether T=-40 - -35°C;
参考文献
Melikyan, Gagik G.; Rivas, Bianca; Harutyunyan, Stepan; Carlson, Louis; Sepanian, Ruth
Organometallics, 2012 , vol. 31, # 5 p. 1653 - 1663
反应条件
copper in acetonitrile 3 h; Heating;
参考文献
Ceylan, Sascha; Klande, Tobias; Vogt, Carla; Friese, Carsten; Kirschning, Andreas
Synlett, 2010 , # 13 p. 2009 - 2013
反应条件
potassium hydroxide T=0°C; anschliessendes Behandeln mit Benzaldehyd;
参考文献
Rutan; May
Journal of the American Chemical Society, 1947 , vol. 69, p. 2017
反应条件
vinyl acetate in dichloromethane T=20°C; 19 h; Inert atmosphere;
参考文献
Siah, Huey-San Melanie; Kaur, Maya; Iqbal, Naseem; Fiksdahl, Anne
European Journal of Organic Chemistry, 2014 , vol. 2014, # 8 p. 1727 - 1740
