1-苯基-2-丙炔-1-醇合成路线 （共 176 条）
反应条件
potassium tert-butylate in toluene
T=100°C; 4 h; Inert atmosphere;
参考文献
Wang, Xu; Pan, Ying-Ming; Huang, Xiao-Chao; Mao, Zhong-Yuan; Wang, Heng-Shan
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 13 p. 2028 - 2032
反应条件
BaMnO4; acetic acid in ethanol
T=150°C; 0.75 h; Microwave irradiation;
参考文献
Bagley, Mark C.; Lin, Zhifan; Pope, Simon J.A.
Tetrahedron Letters, 2009 , vol. 50, # 49 p. 6818 - 6822
反应条件
copper(II) bis(trifluoromethanesulfonate) in chlorobenzene
6 h; Reflux;
参考文献
Lin, Min; Chen, Qing-Zhen; Zhu, Yu; Chen, Xin-Liang; Cai, Ji-Jun; Pan, Ying-Ming; Zhan, Zhuang-Ping
Synlett, 2011 , # 8 art. no. W21010ST, p. 1179 - 1183
反应条件
lithium aluminium tetrahydride; aluminium trichloride
参考文献
Fleming, Steven A.; Carroll, Sean M.; Hirschi, Jennifer; Liu, Renmao; Pace, J. Lee; Redd, J. Ty
Tetrahedron Letters, 2004 , vol. 45, # 17 p. 3341 - 3343
反应条件
titanium(III) chloride; methyllithium in ethylene glycol dimethyl ether; diethyl ether
Further byproducts given;
参考文献
Coulomb-Delbecq,F.; Gore,J.
Bulletin de la Societe Chimique de France, 1976 , p. 541 - 549
反应条件
1.1: potassium carbonate; tetrabutylammomium bromide; copper(l) iodide / N,N-dimethyl-formamide / 0.25 h / 20 °C / |Inert atmosphere
1.2: 24 h / 20 °C / |Inert atmosphere
2.1: manganese(IV) oxide / dichloromethane / 20 °C
3.1: toluene-4-sulfonic acid / methanol / 12 h / 75 °C
View Scheme
参考文献
Yang, Fang; Qiu, Yi-Feng; Ji, Ke-Gong; Niu, Yan-Ning; Ali, Shaukat; Liang, Yong-Min
Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 9029 - 9037,9
反应条件
carbamic acid 1,1-dimethylethyl ester; [Ru(η3-2-C3H4Me)(CO)(1,1'-(Ph2P)2-ferrocene)][SbF6]; trifluoroacetic acid in tetrahydrofuran
T=20 - 75°C; Inert atmosphere;
参考文献
Cadierno, Victorio; Gimeno, Jose; Nebra, Noel
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 1 p. 233 - 236
反应条件
copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
T=120°C; 0.5 h; microwave irradiation;
参考文献
Schramm, Oana G.; Mueller, Thomas J. J.
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 18 p. 2565 - 2570
反应条件
copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
T=120°C; 0.5 h; microwave irradiation;
参考文献
Schramm, Oana G.; Mueller, Thomas J. J.
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 18 p. 2565 - 2570
反应条件
{η5-Ph4C4CO}Ru(CO)3 in toluene
T=100°C; 5 h; Product distribution; Further Variations:Catalysts;
参考文献
Haak, Edgar
Synlett, 2006 , # 12 p. 1847 - 1848
