1-苯基-2-丙炔-1-醇合成路线 （共 176 条）
参考文献
Hennion; Murray
Journal of the American Chemical Society, 1942 , vol. 64, p. 1220
反应条件
carbamic acid 1,1-dimethylethyl ester; [Ru(η3-2-C3H4Me)(CO)(1,1'-(Ph2P)2-ferrocene)][SbF6]; trifluoroacetic acid in tetrahydrofuran
T=20 - 75°C; Inert atmosphere;
参考文献
Cadierno, Victorio; Gimeno, Jose; Nebra, Noel
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 1 p. 233 - 236
反应条件
1: Br2, aq. KOH
2: NH2OH*HCl, CuCl, EtNH2 / methanol
3: (i) SOCl2, Py, Et2O, (ii) Na, EtOH
View Scheme
参考文献
Mavrov,M.V.; Kucherov,V.F.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1966 , p. 833 - 836
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1966 , p. 871 - 874
反应条件
1: Heating
2: MeMgI, MgI2 / diethyl ether
View Scheme
参考文献
Coulomb-Delbecq,F. et al.
Bulletin de la Societe Chimique de France, 1976 , p. 533 - 540
反应条件
1: CuBr; diisopropylamine / dioxane / Heating
2: 62 percent / LiBr; acetic acid / palladium(II) acetate / 1 h / 40 °C
View Scheme
参考文献
De, Subhasis; Day, Cynthia; Welker, Mark E.
Tetrahedron, 2007 , vol. 63, # 45 p. 10939 - 10948
反应条件
1: 3-hydroxy-3-phenyl-prop-1-yne With sodium hydride in tetrahydrofuran
T=0°C; 0.0833333 h; Inert atmosphere;
2: dimethyl sulfate in tetrahydrofuran
2.5 h;
参考文献
UNIVERSITY HEALTH NETWORK; LAUFER, Radoslaw; PAULS, Heinz W.; FEHER, Miklos; NG, Grace; LIU, Yong; EDWARDS, Louise G.; PATEL, Narendra Kumar B.; PAN, Guohua; MAK, Tak W.
Patent: WO2011/123937 A1, 2011 ;
Location in patent: Page/Page column 94 ;
WO 2011/123937 A1
反应条件
NH4BF4; [(η5-C5Me5)RuCl(μ2-SMe)2Ru(η5-C5Me5)Cl]
T=60°C; 0.25 h;
参考文献
Nishibayashi, Yoshiaki; Milton, Marilyn Daisy; Inada, Youichi; Yoshikawa, Masato; Wakiji, Issei; Hidai, Masanobu; Uemura, Sakae
Chemistry - A European Journal, 2005 , vol. 11, # 5 p. 1433 - 1451
反应条件
1: 3-hydroxy-3-phenyl-prop-1-yne With sodium hydride in tetrahydrofuran
T=20°C; 0.166667 h;
2: methyl iodide in tetrahydrofuran
T=20°C;
参考文献
Nielsen, Thomas E.; Le Quement, Sebastian Le; Tanner, David
Synthesis, 2004 , # 9 p. 1381 - 1390
反应条件
in tetrahydrofuran; anhydrous xylene
T=-20°C; 1.5 h; Inert atmosphere;
参考文献
Melikyan, Gagik G.; Rivas, Bianca; Harutyunyan, Stepan; Carlson, Louis; Sepanian, Ruth
Organometallics, 2012 , vol. 31, # 5 p. 1653 - 1663
反应条件
methanol; sulfuric acid
参考文献
Hagihara; Hirao
Memoirs of the Institute of Scientific and Industrial Research, Osaka University, 1950 , vol. 7, p. 133
