4,5-二氯-2-间甲苯吡嗪-3(2H)-酮合成路线 （共 2 条）
反应条件
hydrogenchloride in water T=100°C; 5 h;
参考文献
MEMORIAL SLOAN-KETTERING CANCER CENTER
Patent: WO2008/80056 A2, 2008 ;
Location in patent: Page/Page column 94 ;
反应条件
hydrogenchloride; water 3 h; Reflux;
参考文献
Urbano, Mariangela; Guerrero, Miguel; Zhao, Jian; Velaparthi, Subash; Roberts, Edward; Adrian Saldanha, S.; Chase, Peter; Hodder, Peter; Wang, Zhiwei; Civelli, Olivier; Schaeffer, Marie-Therese; Brown, Steven; Rosen, Hugh
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7135 - 7141,7
