N1-甲基-4-硝基苯-1,2-二胺合成路线 （共 32 条）
参考文献
Brand; Wild
Chemische Berichte, 1923 , vol. 56, p. 110
反应条件
in N,N-dimethyl-formamide
T=20°C; 2 h;
参考文献
AURIGENE DISCOVERY TECHNOLOGIES LIMITED; SENGUPTA, Saumitra; RAJAGOPALAN, Srinivasan; BELAVAGI, Ningaraddi; RAMACHANDRA, Muralidhara
Patent: WO2012/59932 A1, 2012 ;
Location in patent: Page/Page column 163 ;
WO 2012/059932 A1
反应条件
1,1'-carbonyldiimidazole in tetrahydrofuran; water
参考文献
Boehringer Ingelheim Pharma KG
Patent: US6114532 A1, 2000 ;
US 6114532 A
参考文献
van Romburgh; Huyser
Verslag van de Gewone Vergadering van de Afdeling Natuurkunde, Koninklijke Nederlandse Akademie van Wetenschappen, vol. 35, p. 669
Chem. Zentralbl., 1926 , vol. 97, # II p. 2064
参考文献
van Romburgh; Huyser
Recueil des Travaux Chimiques des Pays-Bas, 1930 , vol. 49, p. 165,175
参考文献
van Romburgh; Huyser
Recueil des Travaux Chimiques des Pays-Bas, 1930 , vol. 49, p. 165,175
反应条件
1: anschliessend Behandeln mit konz. Salzsaeure
2: concentrated sulfuric acid; red fuming nitric acid
View Scheme
参考文献
Fries
Justus Liebigs Annalen der Chemie, 1927 , vol. 454, p. 204
反应条件
1: methanol / Reflux
2: hydrogen / methanol / 20 °C / 1500.15 Torr
View Scheme
参考文献
Bella, Maros; Milata, Viktor; Larina, Lyudmila I.
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 293 - 296
反应条件
1: in pyridine
T=80°C; 0.5 h;
2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in pyridine
T=15 - 80°C; 16 h;
参考文献
METHYLGENE INC.
Patent: WO2005/92899 A1, 2005 ;
Location in patent: Page/Page column 156-157 ;
参考文献
Phillips
Journal of the Chemical Society, 1930 , p. 1409,1413
