3,4-吡咯二羧酸二乙酯合成路线 （共 15 条）
反应条件
sodium hydride in 1-methyl-pyrrolidin-2-one
参考文献
Walter, Harald
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2008 , vol. 63, # 4 p. 351 - 362
反应条件
1.1: NaH / dimethylformamide / 0.5 h / 20 °C
1.2: dimethylformamide / 20 °C
2.1: PTSA / acetone; H2O
View Scheme
参考文献
Blot, Virginie; Reissig, Hans-Ulrich
European Journal of Organic Chemistry, 2006 , # 22 p. 4989 - 4992
反应条件
sodium hydroxide in ethanol; water
2 h; Heating;
参考文献
Kaesler, Ralph W.; LeGoff, Eugene
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4399 - 4402
反应条件
1: 95 percent / NaOH / ethanol; H2O / 2 h / Heating
2: oxalyl chloride, DMF / toluene / 0.83 h / 85 °C
View Scheme
参考文献
Kaesler, Ralph W.; LeGoff, Eugene
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4399 - 4402
反应条件
1: sodium hydroxide / 1,2-dichloro-ethane / 48 h / 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 0.17 h / 0 °C
3: phosphorus tribromide / dichloromethane / 0 - 20 °C / Inert atmosphere
View Scheme
参考文献
Kim, Sung Kuk; Gross, Dustin E.; Cho, Dong-Gyu; Lynch, Vincent M.; Sessler, Jonathan L.
Journal of Organic Chemistry, 2011 , vol. 76, # 4 p. 1005 - 1012
