1: With N-(diphenylmethylene)amine; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0) in toluene T=80°C; 1.5 h; Inert atmosphere; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; 3 h;

ammonia; sodium in sodium hydroxide; N,N-dimethyl-aniline

sodium amide in various solvent(s) 1.)r.t. 2.)175 deg C, 18 h;

1: CH2Cl2 / Heating 2: conc. HCl View Scheme