1: With LiNH2 in tetrahydrofuran T=30 - 50°C; 4 h; Inert atmosphereLarge scale; 2: With hydrogenchloride in tetrahydrofuran; water T=50°C; Inert atmosphereLarge scale; SolventTemperatureReagent/catalyst;
参考文献
Davis, Edward M.; Nanninga, Thomas N.; Tjiong, Howie I.; Winkle, Derick D.
Organic Process Research and Development, 2005 , vol. 9, # 6 p. 843 - 846