3-(甲基氨基)-1-丙醇合成路线 (共 24 条)
反应条件
1-methylimidazolium tetrafluoroborate T=30 - 35°C; 0.0833333 h;
参考文献
Tetrahedron Letters, , vol. 49, # 16 p. 2527 - 2532
反应条件
1: N-3-hydroxypropyl-N-methylamine With sodium hydride in dimethyl sulfoxide T=20°C; 1 h; 2: (S)-5-chloro-6-(2,4,6-trifluorophenyl)-N-(1,1,1-trifluoropropan-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine in dimethyl sulfoxide T=60°C; 3 h;
参考文献
Zhang, Nan; Ayral-Kaloustian, Semiramis; Nguyen, Thai; Afragola, Jay; Hernandez, Richard; Lucas, Judy; Gibbons, James; Beyer, Carl
Journal of Medicinal Chemistry, 2007 , vol. 50, # 2 p. 319 - 327
参考文献
Lann, Martine Le; Saba, Shahrokh; Shoja, Massud
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1789 - 1794
参考文献
Bristol-Myers Squibb Company
Patent: US6255496 B1, 2001 ;