(2E)-3-(4-氧代-4H-苯并吡喃-3-基)丙烯酸合成路线 （共 5 条）
反应条件
pyridine in tetrahydrofuran
T=50 - 60°C; 2 h;
参考文献
Shutov, Roman V.; Kuklina, Elizaveta V.; Ivin, Boris A.
Tetrahedron Letters, 2011 , vol. 52, # 2 p. 266 - 269
反应条件
alum
Doebner-Knoevenagel reaction; 0.0666667 h; Microwave irradiation;
参考文献
Suresh, Dhruva Kumar; Sandhu, Jagir S.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 10 p. 1479 - 1483
反应条件
sulfuric acid
1.5 h; Heating;
参考文献
Iwasaki, Hideharu; Kume, Takashi; Yamamoto, Yohsuke; Akiba, Kin-ya
Heterocycles, 1988 , vol. 27, # 7 p. 1599 - 1602
反应条件
1: 96 percent / 2,6-lutidine / CH2Cl2 / 1 h / Heating
2: 0.17 h / 80 °C
3: 1 h / Ambient temperature
4: 98 percent / 1.6 M H2SO4 / 1.5 h / Heating
View Scheme
参考文献
Iwasaki, Hideharu; Kume, Takashi; Yamamoto, Yohsuke; Akiba, Kin-ya
Heterocycles, 1988 , vol. 27, # 7 p. 1599 - 1602
反应条件
1: 0.17 h / 80 °C
2: 1 h / Ambient temperature
3: 98 percent / 1.6 M H2SO4 / 1.5 h / Heating
View Scheme
参考文献
Iwasaki, Hideharu; Kume, Takashi; Yamamoto, Yohsuke; Akiba, Kin-ya
Heterocycles, 1988 , vol. 27, # 7 p. 1599 - 1602
