8-氯-5-甲氧基-2-甲基喹啉合成路线 （共 2 条）
反应条件
hydrogenchloride in water; toluene
Skraup reaction; 1 h; Reflux;
参考文献
Li, Jianke; Kung, Daniel W.; Griffith, David A.
Tetrahedron Letters, 2010 , vol. 51, # 30 p. 3876 - 3878
反应条件
1: With hydrogen bromide in water
20 h; Heating / reflux;
2: With sodium hydrogencarbonate in water
参考文献
GLAXO GROUP LIMITED
Patent: WO2004/46124 A1, 2004 ;
Location in patent: Page 45 ;
WO 2004/046124 A1
