(3-肼基-3-氧代丙基)氨基甲酸叔丁酯合成路线 （共 4 条）
反应条件
hydrazine hydrate
T=20°C; Reflux;
参考文献
Jansen, Michaela; Rabe, Holger; Strehle, Axelle; Dieler, Sandra; Debus, Fabian; Dannhardt, Gerd; Akabas, Myles H.; Lueddens, Hartmut
Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4430 - 4448
反应条件
hydrazine in ethanol
24 h; Heating / reflux;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2006/62224 A1, 2006 ;
Location in patent: Page/Page column 81 ;
反应条件
hydrazine hydrate in methanol
T=70°C; 16 h; Inert atmosphere;
参考文献
Poojari, Subba; Naik, Parameshwar; Krishnamurthy
Tetrahedron Letters, 2014 , vol. 55, # 2 p. 305 - 309
反应条件
(i) Py, (ii) N2H4*H2O, MeOH; Multistep reaction;
参考文献
Portelli,M.; Renzi,G.
Farmaco, Edizione Scientifica, 1973 , vol. 28, p. 316 - 322
