2-氨基-3,5二氯吡啶合成路线 （共 25 条）
反应条件
sodium hydride in N,N-dimethyl-formamide
5 h; Ambient temperature;
参考文献
Ferranti; Garuti; Giovanninetti; Borgatti; Bartoletti
Archiv der Pharmazie, 1985 , vol. 318, # 1 p. 78 - 84
反应条件
in glycerol
0.25 - 0.333333 h; Microwave irradiation;
参考文献
Kaloyanova, Stefka; Crnolatac, Ivo; Lesev, Nedyalko; Piantanida, Ivo; Deligeorgiev, Todor
Dyes and Pigments, 2012 , vol. 92, # 3 p. 1184 - 1191
反应条件
in dichloromethane
T=40°C; 3 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; MCDONALD, Ivar M.; MATE, Robert A.; COOK II, James H.; KING, Dalton; OLSON, Richard E.; WANG, Nenghui; IWUAGWU, Christiana I.; ZUSI, F. Christopher; HILL, Matthew D.; FANG, Haiquan; MACOR, John E.
Patent: WO2011/56503 A1, 2011 ;
Location in patent: Page/Page column 41-42 ;
WO 2011/056503 A1
参考文献
Beecham Group Limited
Patent: US4224331 A1, 1980 ;
反应条件
in dichloromethane
T=0°C; 0.75 h;
参考文献
Khan, Khalid Mohammed; Naz, Farzana; Taha, Muhammad; Khan, Ajmal; Perveen, Shahnaz; Choudhary; Voelter, Wolfgang
European Journal of Medicinal Chemistry, 2014 , vol. 74, p. 314 - 323
