(R)-(+)-萘基-1-乙醇合成路线 （共 74 条）
反应条件
sodium formate; N-hexadecyl-N,N,N-trimethylammonium bromide; [RuCl(η6-p-cymene)(N-tosyl-1,2-diphenylethylenediamine)] in water T=28°C; 10 h; Title compound not separated from byproducts;
参考文献
Wang, Fei; Liu, Hui; Cun, Linfeng; Zhu, Jin; Deng, Jingen; Jiang, Yaozhong
Journal of Organic Chemistry, 2005 , vol. 70, # 23 p. 9424 - 9429
反应条件
iodosylbenzene; iron(III) meso-tetraphenylporhinato chloride in dichloromethane T=0°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Groves, John T.; Viski, Peter
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3628 - 3634
反应条件
4 A molecular sieve; Lipase from Burkholderia cepacia in 1,4-dioxane T=30°C; 48 h;
参考文献
Savile, Christopher K.; Kazlauskas, Romas J.
Journal of the American Chemical Society, 2005 , vol. 127, # 35 p. 12228 - 12229
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Naemura, Koichiro; Nishioka, Kazuyuki; Ogasahara, Kazuko; Nishikawa, Yasushi; Hirose, Keiji; Tobe, Yoshito
Tetrahedron Asymmetry, 1998 , vol. 9, # 4 p. 563 - 574
反应条件
4 A molecular sieve; subtilisin Carlsberg in 1,4-dioxane T=30°C; 48 h; Title compound not separated from byproducts;
参考文献
Savile, Christopher K.; Kazlauskas, Romas J.
Journal of the American Chemical Society, 2005 , vol. 127, # 35 p. 12228 - 12229
反应条件
1: methylmagnesium bromide With titanium(IV) isopropylate; bis[2-(N,N-dimethylamino)ethyl] ether; (S)-(minus;)-1,1'-bi-2-naphthol in tetrahydrofuran; tert-butyl methyl ether T=20°C; Inert atmosphereCooling with ice; 2: 1-naphthaldehyde in tetrahydrofuran; tert-butyl methyl ether T=20°C; Inert atmosphereCooling with ice; optical yield given as percent eeenantioselective reaction;
参考文献
Liu, Yi; Da, Chao-Shan; Yu, Sheng-Li; Yin, Xiao-Gang; Wang, Jun-Rui; Fan, Xin-Yuan; Li, Wei-Ping; Wang, Rui
Journal of Organic Chemistry, 2010 , vol. 75, # 20 p. 6869 - 6878
反应条件
Rhizopus nigricans (sterile potato dextrose medium) in tetrahydrofuran 16 h;
参考文献
Ziffer, Herman; Kawai, Ken-ichi; Kasai, Masaji; Imuta, Mitsuru; Froussios, Cleanthis
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3017 - 3021
反应条件
endo-8,8-dimethyl-2-phenylphosphabicyclo[3.3.0]-octane in toluene T=-25°C; Activation energyProduct distribution; Further Variations:ReagentsTemperatures;
参考文献
MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6934 - 6937
反应条件
(2S,3R)-3-isopropyl-2-phenyl-3,4-dihydro-2H-pyrimido[2,1-b]benzothiazole; N-ethyl-N,N-diisopropylamine in toluene T=-40°C; 1 h; optical yield given as percent eeenantioselective reaction;
参考文献
Belmessieri, Dorine; Joannesse, Caroline; Woods, Philip A.; MacGregor, Callum; Jones, Caroline; Campbell, Craig D.; Johnston, Craig P.; Duguet, Nicolas; Concellon, Carmen; Bragg, Ryan A.; Smith, Andrew D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 2 p. 559 - 570
反应条件
potassium hydroxide 3 h; Ambient temperature;
参考文献
Theisen, Peter D.; Heathcock, Clayton H.
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2374 - 2378
