(R)-(+)-萘基-1-乙醇合成路线 （共 74 条）
反应条件
C9H21ClO3Ti*C9H18O2 in tetrahydrofuran Yield given. Yields of byproduct given;
参考文献
Muramatsu, Yusuke; Kanehira, Shinichi; Tanigawa, Masato; Miyawaki, Yuta; Harada, Toshiro
Bulletin of the Chemical Society of Japan, 2010 , vol. 83, # 1 p. 19 - 32
反应条件
triethylamine; (-)-diethyl[3-(2-phenylnaphthyl)(4-pyridyl)]amine in toluene T=-78°C; 9 h; Title compound not separated from byproducts;
参考文献
Spivey, Alan C.; Zhu, Fujiang; Mitchell, Mark B.; Davey, Stephen G.; Jarvest, Richard L.
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7379 - 7385
反应条件
triethylamine; (-)-diethyl[3-(2-phenylnaphthyl)(4-pyridyl)]amine in toluene T=-78°C; 9 h; Title compound not separated from byproducts;
参考文献
Spivey, Alan C.; Zhu, Fujiang; Mitchell, Mark B.; Davey, Stephen G.; Jarvest, Richard L.
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7379 - 7385
反应条件
chiral substituted phosphabicyclo[3.3.0]octane*HBF4; triethylamine in 1,1-dimethylpropan-1-ol; dichloromethane T=-25°C; 15 h; Title compound not separated from byproducts;
参考文献
MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6934 - 6937
反应条件
1: diethyl ether / 2.5 h / 0 - 20 °C 2: IL1 / lipase PS-C / diisopropyl ether / 24 h / 35 °C View Scheme
参考文献
Itoh, Toshiyuki; Matsushita, Yuichi; Abe, Yoshikazu; Han, Shi-Hui; Wada, Shohei; Hayase, Shuichi; Kawatsura, Motoi; Takai, Shigeomi; Morimoto, Minoru; Hirose, Yoshihiko
Chemistry - A European Journal, 2006 , vol. 12, # 36 p. 9228 - 9237
反应条件
vinyl acetate; 4 Anstroem molecular sives; lipase LIP in di-isopropyl ether T=30°C; 3 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kato; Katayama; Fujii; Kimoto
Bioscience, biotechnology, and biochemistry, 1995 , vol. 59, # 11 p. 2178 - 2180
反应条件
sodium hydroxide in methanol 0.0833333 h; Heating;
参考文献
Duffey, Trisha A.; MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2010 , vol. 75, # 14 p. 4674 - 4685
反应条件
1: 95 percent / PPTS / CH2Cl2 / 12 h / Ambient temperature 2: DIBALH / toluene / 0.5 h / -78 °C View Scheme
参考文献
Dirat, Olivier; Kouklovsky, Cyrille; Langlois, Yves
Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6634 - 6642
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=20°C; Inert atmosphereAnhydrous conditions; optical yield given as percent ee;
参考文献
Leclercq, Loic; Suisse, Isabelle; Agbossou-Niedercorn, Francine
European Journal of Organic Chemistry, 2010 , # 14 p. 2696 - 2700
反应条件
(R)-(+)-N-methylbenzoguanidine; trimethylacetic anhydride in diethyl ether T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Nakata, Kenya; Shiina, Isamu
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 7092 - 7096
