(R)-(+)-萘基-1-乙醇合成路线 （共 74 条）
反应条件
Na-Pi buffer in acetone 48 h; tubers of Helianthus tuberosus presence, pH 5.9; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Mironowicz, Agnieszka
Phytochemistry, 1998 , vol. 47, # 8 p. 1531 - 1534
反应条件
methanol; sodium hydroxide T=20°C; Inert atmosphereHeating; optical yield given as percent ee;
参考文献
Duffey, Trisha A.; MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2010 , vol. 75, # 14 p. 4674 - 4685
反应条件
methanol; sodium hydroxide T=20°C; Inert atmosphereHeating; optical yield given as percent ee;
参考文献
Duffey, Trisha A.; MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2010 , vol. 75, # 14 p. 4674 - 4685
反应条件
1: triethylamine; 4-(N,N-dimethlyamino)pyridine / diethyl ether 2: sodium carbonate / toluene / 72 h / 40 °C / |Schlenk technique; |Resolution of racemate; |Enzymatic reaction View Scheme
参考文献
Houiene, Zahia; Merabet-Khelassi, Mounia; Bouzemi, Nassima; Riant, Olivier; Aribi-Zouioueche, Louisa
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 290 - 296
反应条件
C50H42ClN2O3Ru in chloroform T=25°C; Molecular sieveResolution of racemate; Kinetics; enantioselective reaction;
参考文献
Mizoguchi, Hirotaka; Uchida, Tatsuya; Katsuki, Tsutomu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3178 - 3182
Angew. Chem., 2014 , vol. 126, # 12 p. 3242 - 3246,5
反应条件
C22H29N3O3; triethylamine; C16H23P*BF4(1-)*H(1+) in toluene T=-40°C; 3 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Duffey, Trisha A.; MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2010 , vol. 75, # 14 p. 4674 - 4685
反应条件
1: triethylamine; 4-(N,N-dimethlyamino)pyridine / diethyl ether 2: sodium carbonate / toluene / 72 h / 40 °C / |Schlenk technique; |Resolution of racemate; |Enzymatic reaction View Scheme
参考文献
Houiene, Zahia; Merabet-Khelassi, Mounia; Bouzemi, Nassima; Riant, Olivier; Aribi-Zouioueche, Louisa
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 290 - 296
反应条件
Y(salen)(N(SiMe2H)2)(THF) in toluene T=-3°C; 17 h; Product distribution; Further Variations:CatalystsReaction partnersSolventsReagentstimes;
参考文献
Lin, Mei-Huey; RajanBabu
Organic Letters, 2002 , vol. 4, # 9 p. 1607 - 1610
反应条件
endo-8,8-dimethyl-2-phenylphosphabicyclo[3.3.0]-octane in toluene T=-25°C; Activation energyProduct distribution; Further Variations:ReagentsTemperaturesSolvents;
参考文献
MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2006 , vol. 71, # 2 p. 498 - 503
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C / |Inert atmosphere 2: lipase from candida antartica / aq. phosphate buffer / 48 h / 30 °C View Scheme
参考文献
Kataoka, Noriyuki; Okudomi, Masayuki; Chihara, Naoka; Matsumoto, Kazutsugu
Letters in Organic Chemistry, 2012 , vol. 9, # 9 p. 615 - 621
