1,3-苯并噻唑-2-甲胺合成路线 （共 11 条）
反应条件
hydrogen bromide in acetic acid
T=20°C; 1.5 h;
参考文献
Salvadori, Severo; Fiorini, Stella; Trapella, Claudio; Porreca, Frank; Davis, Peg; Sasaki, Yusuke; Ambo, Akihiro; Marczak, Ewa D.; Lazarus, Lawrence H.; Balboni, Gianfranco
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 6 p. 3032 - 3038
反应条件
1: 0.33 h / 60 °C
2: Sn, aq. HCl / Heating
View Scheme
参考文献
Kiprianov,A.I.; Verbovskaya,T.M.
J. Gen. Chem. USSR (Engl. Transl.), 1962 , vol. 32, p. 3703,3630 - 3634
反应条件
1: NaNO2 / aq. HCl / 1 h
2: aq. NaOH / 0.17 h / 95 °C
3: Pd/C / methanol / 0.42 h
4: aq. HCl / methanol; H2O / 0.08 h / Ambient temperature
View Scheme
参考文献
Baudet,P.; Otten,C.
Helvetica Chimica Acta, 1970 , vol. 53, p. 1683 - 1693
反应条件
1: Pd/C / methanol / 0.42 h
2: aq. HCl / methanol; H2O / 0.08 h / Ambient temperature
View Scheme
参考文献
Baudet,P.; Otten,C.
Helvetica Chimica Acta, 1970 , vol. 53, p. 1683 - 1693
反应条件
1: aq. NaOH / 0.17 h / 95 °C
2: Pd/C / methanol / 0.42 h
3: aq. HCl / methanol; H2O / 0.08 h / Ambient temperature
View Scheme
参考文献
Baudet,P.; Otten,C.
Helvetica Chimica Acta, 1970 , vol. 53, p. 1683 - 1693
反应条件
hydrazine hydrate in ethanol
1.5 h; Heating;
参考文献
Ozawa, Tomohiro; Kitagawa, Hideo; Yamamoto, Yasuo; Takahata, Sho; Iida, Maiko; Osaki, Yumi; Yamada, Keiko
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 23 p. 7325 - 7336
反应条件
hydrogenchloride in methanol; water
0.0833333 h; Ambient temperature;
参考文献
Baudet,P.; Otten,C.
Helvetica Chimica Acta, 1970 , vol. 53, p. 1683 - 1693
反应条件
hydrogenchloride; tin
参考文献
Kiprianow; Werbeowskaja
Zhurnal Obshchei Khimii, 1962 , vol. 32, p. 3703,3706; engl. Ausg. S. 3630, 3633
反应条件
sodium azide; ethanol; acetic acid
Behandeln des erhaltenen 2-Azidomethyl-benzothiazols mit Zink und wss. HCl;
参考文献
Kiprianow; Potschinok
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1953 , vol. 19, p. 165
Chem. Zentralbl., 1956 I 3299
反应条件
hydrogenchloride
Heating;
参考文献
Arnone,A. et al.
Gazzetta Chimica Italiana, 1973 , vol. 103, p. 13 - 29
