2,2-二氯-3,3,3-三氟丙酸合成路线 (共 3 条)
反应条件
1: 1,1,1-trichloro-2,2,2-trifluoro-ethane With zinc in N,N-dimethyl-formamide T=20°C; Metallation; 1 h; 2: carbon dioxide in N,N-dimethyl-formamide Carboxylation; 18 h;
参考文献
Johnson, Theodore R.; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1625 - 1636
反应条件
water; hydrogen cation; zinc in N,N-dimethyl-formamide 6 h; irradiated by ultrasound;
参考文献
Hemer,I.; Havlicek,J.
Journal of Fluorine Chemistry, 1986 , vol. 34, p. 241
参考文献
Park et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 220