lithium azide in N,N-dimethyl-formamide T=20°C; 48 h; Inert atmosphere;

ammonia in methanol 16 h; Ambient temperature;

1: 94 percent / NaN3 / dimethylformamide / 4 h / 85 °C 2: 84 percent / pyridine / 26 h / 0 - 20 °C 3: 1.) (NH4)2SO4, hexamethyldisilazane, 2.) trimethylsilyl triflate / 1.) reflux, overnight, 2.) MeCN, from -40 deg C to 0 deg C, 4 h 4: ammonia / methanol / 16 h / Ambient temperature View Scheme

1: 1.) (NH4)2SO4, hexamethyldisilazane, 2.) trimethylsilyl triflate / 1.) reflux, overnight, 2.) MeCN, from -40 deg C to 0 deg C, 4 h 2: ammonia / methanol / 16 h / Ambient temperature View Scheme

1: 84 percent / pyridine / 26 h / 0 - 20 °C 2: 1.) (NH4)2SO4, hexamethyldisilazane, 2.) trimethylsilyl triflate / 1.) reflux, overnight, 2.) MeCN, from -40 deg C to 0 deg C, 4 h 3: ammonia / methanol / 16 h / Ambient temperature View Scheme