(S)-(+)-2-丁醇合成路线 （共 56 条）
反应条件
triphenylphosphine; diethylazodicarboxylate in dichloromethane T=-23 - 20°C; Mitsunobu reaction;
参考文献
Chandrasekhar, Sosale; Kulkarni, Guruprasad
Tetrahedron Asymmetry, 2002 , vol. 13, # 6 p. 615 - 619
反应条件
in methanol; water Resolution of racemate; optical yield given as percent ee;
参考文献
Akazome, Motohiro; Toma, Shusaku; Horiguchi, Tatsunori; Megumi, Ken; Matsumoto, Shoji
Tetrahedron, 2011 , vol. 67, # 16 p. 2844 - 2848
反应条件
methylmagnesium bromide; copper (I) cyanide in tetrahydrofuran; diethyl ether T=-35 - 20°C; 1.5 h; Inert atmosphere;
参考文献
Taguri, Tomonori; Yamamoto, Masanobu; Fujii, Toru; Muraki, Yuta; Ando, Tetsu
European Journal of Organic Chemistry, 2013 , # 30 p. 6924 - 6933
反应条件
sodium hydroxide; (-)-isopinocampheylborane; dihydrogen peroxide multistep reaction: enantioselectivity; other trans alkenes;
参考文献
Dhokte, Ulhas P.; Brown, Herbert C.
Tetrahedron Letters, 1994 , vol. 35, # 27 p. 4715 - 4718
反应条件
platinum(IV) oxide Hydrogenation.durch Druckhydrierung;
参考文献
Morell; Auernheimer
Journal of the American Chemical Society, 1944 , vol. 66, p. 794
反应条件
Pseudomonas cepacia lipase in di-isopropyl ether T=30°C; Esterification; Racemate separation; 20 h; Title compound not separated from byproducts;
参考文献
Athawale, Vilas; Manjrekar, Narendra
Synlett, 2000 , # 2 p. 225 - 226
反应条件
montmorilonite K10 T=60°C; 0.333333 h; Product distribution / selectivity;
参考文献
MONASH UNIVERSITY
Patent: WO2005/70911 A1, 2005 ;
Location in patent: Page/Page column 91-92 ;
反应条件
sodium hydroxide; dihydrogen peroxide in tetrahydrofuran
参考文献
Brown, Herbert C.; Jadhav, Prabhakar K.; Desai, Manoj C.
Tetrahedron, 1984 , vol. 40, # 8 p. 1325 - 1332
反应条件
Lactobacillus brevis (LB-5) T=30°C; 168 h; Title compound not separated from byproducts;
参考文献
Speranza, Giovanna; Corti, Sandra; Fontana, Gabriele; Manitto, Paolo; Galli, Antonietta; Scarpellini, Mauro; Chialva, Franco
Journal of Agricultural and Food Chemistry, 1997 , vol. 45, # 9 p. 3476 - 3480
反应条件
phosphate buffer; almond-β-glucosidase T=37°C; pH=6.0; 24 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Shimoda, Kei; Kubota, Naoji; Hamada, Hiroki
Tetrahedron Asymmetry, 2004 , vol. 15, # 15 p. 2319 - 2321
