2-羟基-2-甲氧基chalc酮合成路线 （共 6 条）
反应条件
sodium hydroxide; dihydrogen peroxide in ethanol; water Algar-Flynn-Olyamada (AFO) reaction;
参考文献
Li, Zhitao; Ngojeh, George; DeWitt, Paul; Zheng, Zhi; Chen, Min; Lainhart, Brendan; Li, Vincent; Felpo, Peter
Tetrahedron Letters, 2008 , vol. 49, # 51 p. 7243 - 7245
反应条件
iodine in dimethyl sulfoxide
T=140°C;
参考文献
Kralj, Ana; Nguyen, Mai-Thao; Tschammer, Nuska; Ocampo, Nicolette; Gesiotto, Quinto; Heinrich, Markus R.; Phanstiel, Otto
Journal of Medicinal Chemistry, 2013 , vol. 56, # 12 p. 5019 - 5032
反应条件
NiO2 in 1,4-dioxane
T=100°C; 18 h;
参考文献
Mallik, Uttam K.; Murari, M. Saha; Mallik, Asok K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 970 - 972
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane
72 h; Heating;
参考文献
Imafuku, Kimiaki; Honda, Masaaki; McOmie, J. F. W.
Synthesis, 1987 , # 2 p. 199 - 201
反应条件
sodium tetrahydroborate in isopropyl alcohol
参考文献
Maiti, Gourhari; Kayal, Utpal; Karmakar, Rajiv; Bhattacharya, Rudraksha N.
Tetrahedron Letters, 2012 , vol. 53, # 47 p. 6321 - 6325,5
反应条件
1: 3.5 g / 30 percent H2O2; NaOEt / ethanol / 0 - 20 °C
2: 46 percent / 57 percent aq. HI / Heating
View Scheme
参考文献
Sobottka; Werner; Blaschke; Kiefer; Nowe; Dannhardt; Schapoval; Schenkel; Scriba
Archiv der Pharmazie, 2000 , vol. 333, # 7 p. 205 - 210
