反应条件
1: conc. H2SO4 / 4 h / Ambient temperature
2: KOH, hydrazine hydrate / bis-(2-hydroxy-ethyl) ether / 2 h / Heating
3: toluene / 0.5 h / Heating
4: polyphosphoric acid / 1 h / 130 °C
5: POCl3, N,N-dimethylaniline / 3 h / Heating
6: dioxane / 6 h / Heating
View Scheme
参考文献
Hunziker; Fischer; Kipfer; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 5 p. 391 - 398