3-(4-甲氧基苯基)环氧乙烷-2-甲酸甲酯合成路线 （共 10 条）
反应条件
1: 77 percent / 50percent NaOH / benzyltriethylammonium chloride / benzene; H2O / 1 h / 5 - 10 °C 2: 1) K2CO3; 2) HCl/H2O / 1) 20 deg C, 3 h; 2) 0 to 5 deg C, 2 h View Scheme
参考文献
Svoboda, Jiri; Kocfeldova, Zuzana; Palecek, Jaroslav
Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 4 p. 822 - 832
反应条件
sodium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide Ambient temperature;
参考文献
Hashiyama, Tomiki; Inoue, Hirozumi; Konda, Mikihiko; Takeda, Mikio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1725 - 1732
反应条件
1: 95 percent / OsO4, N-methylmorpholine N-oxide, / acetone; H2O; 2-methyl-propan-2-ol / 24 h / Ambient temperature 2: 60 percent / pyridine / CH2Cl2 / 24 h / 0 °C 3: 95 percent / benzyltrimethylammonium hydroxide / tetrahydrofuran; methanol / 1 h / Ambient temperature View Scheme
参考文献
Brown, Roger. F. C.; Jackson, W. Roy; McCarthy, Tom D.; Fallon, Gary D.
Australian Journal of Chemistry, 1992 , vol. 45, # 11 p. 1833 - 1843
反应条件
hydrogenchloride; water; potassium carbonate 1) 20 deg C, 3 h; 2) 0 to 5 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Svoboda, Jiri; Kocfeldova, Zuzana; Palecek, Jaroslav
Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 4 p. 822 - 832
反应条件
T=165°C; 6 h; Yield given. Yields of byproduct given;
参考文献
Hashiyama, Tomiki; Inoue, Hirozumi; Konda, Mikihiko; Takeda, Mikio
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1256 - 1259
参考文献
Kumaradhas; Nirmala; Sridhar
Acta Crystallographica, Section C: Crystal Structure Communications, 1996 , vol. 52, # pt 10 p. 2595 - 2597
反应条件
Sn(II) (2-ethylhexanoate)2 in 1,4-dioxane 18 h; Ambient temperature; Yields of byproduct given;
参考文献
Hashiyama, Tomiki; Inoue, Hirozumi; Konda, Mikihiko; Takeda, Mikio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1725 - 1732
反应条件
sodium methylate; acetic acid 1.) CH3OH, benzene, 0-5 deg C, 2.) reflux, 3 h; Multistep reaction;
参考文献
Cragg, John E.; Herbert, Richard B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2487 - 2490
反应条件
water in acetone T=25°C; Rhizopus arrhizus mycelium lipase, pH 7;
参考文献
Laffitte, J A; Gancet, C; Soccol, C
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 1 p. 94 - 95
参考文献
Laffitte, J A; Gancet, C; Soccol, C
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 1 p. 94 - 95
