2-[(2S)-1-甲基吡咯烷-2-基]乙胺合成路线 （共 3 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=0°C; 0.25 h; Heating / reflux;
参考文献
Maruha Corporation
Patent: EP1408030 A1, 2004 ;
Location in patent: Page 21 ;
反应条件
1: With hydrogenchloride in tert-butyl methyl ether; water
0.75 h;
2: With sodium hydroxide in water
1.16667 h;
参考文献
SANOFI; ELENBAAS, Steven
Patent: WO2011/109675 A2, 2011 ;
Location in patent: Page/Page column 11-12 ;
反应条件
1.1: ethanol; water / 0.5 h / 65 °C / Inert atmosphere; Industry scale
2.1: hydrogenchloride / water; tert-butyl methyl ether / 0.75 h
2.2: 1.17 h
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参考文献
SANOFI; ELENBAAS, Steven
Patent: WO2011/109675 A2, 2011 ;
