1-苯甲酰-1H-苯并三唑合成路线 （共 99 条）
反应条件
zinc dibromide
1.) THF, ether, 20 deg C, 30 min, 2.) THF, ether, a) 0 deg C 30 min, b) 20 deg C, 5 h; Yield given. Multistep reaction;
参考文献
Katritzky, Alan R.; Moutou, Jean-Luc; Yang, Zhijun
Organic Preparations and Procedures International, 1995 , vol. 27, # 3 p. 361 - 366
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydroxide
1) water + CH2Cl2, 20 deg C, 2 h; 2) CH2Cl2, 20 deg C, 3 h.; Yield given. Multistep reaction;
参考文献
Myznikov, Yu. E.; Koldobskii, G. I.; Vasil'eva, I. N.; Ostrovskii, V. A.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 7 p. 1397 - 1401
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 7 p. 1550 - 1555
参考文献
Gaylord
Journal of the American Chemical Society, 1954 , vol. 76, p. 285
参考文献
Gaylord; Naughton
Journal of Organic Chemistry, 1957 , vol. 22, p. 1022,1023
反应条件
in tetrahydrofuran
T=20°C; 5 h;
参考文献
Wang, Xiaoxia; Yu, Hongping; Xu, Peifang; Zheng, Renwei
Journal of Chemical Research, 2005 , # 9 p. 595 - 597
反应条件
hydroxymethanesulfinic acid sodium salt; potassium carbonate in N,N-dimethyl-formamide
T=20°C; 0.0833333 h;
参考文献
Lin, Shao-Miao; Zhang, Ji-Lei; Chen, Jiu-Xi; Gao, Wen-Xia; Ding, Jin-Chang; Su, Wei-Ke; Wu, Hua-Yue
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 9 p. 1616 - 1620
反应条件
1.1: iPr2NLi / tetrahydrofuran / 1.75 h / -78 °C
1.2: 65 percent / tetrahydrofuran / -78 - 20 °C
2.1: NaH / tetrahydrofuran / 0.67 h / 20 °C
2.2: 52 percent / tetrahydrofuran / 360 h / 20 °C
3.1: 15 percent / toluene / 0.5 h / Heating
View Scheme
参考文献
Katritzky, Alan R.; Wang, Zuoquan; Wang, Mingyi; Hall, C. Dennis; Suzuki, Kazuyuki
Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4854 - 4856
反应条件
1: 2-methyl-3-oxobutanoic acid ethyl ester With sodium hydride in tetrahydrofuran
T=20°C; 0.666667 h;
2: PhCOBt in tetrahydrofuran
T=20°C;
参考文献
Katritzky, Alan R.; Wang, Zuoquan; Wang, Mingyi; Wilkerson, Chavon R.; Hall, C. Dennis; Akhmedov, Novruz G.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6617 - 6622
反应条件
1: acetylacetone With sodium hydride in tetrahydrofuran
T=20°C; 0.666667 h;
2: PhCOBt in tetrahydrofuran
T=20°C; 14 h;
3: With hydrogenchloride in tetrahydrofuran
参考文献
Katritzky, Alan R.; Wang, Zuoquan; Wang, Mingyi; Wilkerson, Chavon R.; Hall, C. Dennis; Akhmedov, Novruz G.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6617 - 6622
反应条件
1: 26 percent / benzene / 24 h / Irradiation
2: CH3COONa
View Scheme
参考文献
Parshad; Sharma
Journal of the Indian Chemical Society, 1990 , vol. 67, # 2 p. 150 - 152
