2-氨基-4-氯二苯基硫化物合成路线 （共 4 条）
反应条件
hydrogenchloride; iron in ethanol
1 h; Heating;
参考文献
ALLERGAN, INC.; YUAN, HAIQING; BEARD, RICHARD L.; LIU, XIAOXIA; DONELLO, JOHN E.; VISWANATH, VEENA; GARST, MICHAEL E.
Patent: US2013/231338 A1, 2013 ;
Location in patent: Paragraph 0344; 0345; 0346 ;
反应条件
1: 90 percent / NaOH / ethanol / 1 h / Heating
2: 96 percent / hydrazine hydrate; Raney-Ni / 2 h / Heating
View Scheme
参考文献
Parveen, Seheli; Khan, Mohammed O. F.; Austin, Susan E.; Croft, Simon L.; Yardley, Vanessa; Rock, Peter; Douglas, Kenneth T.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 25 p. 8087 - 8097
反应条件
1: 90 percent / NaOH / ethanol / 1 h / Heating
2: 96 percent / hydrazine hydrate; Raney-Ni / 2 h / Heating
View Scheme
参考文献
Parveen, Seheli; Khan, Mohammed O. F.; Austin, Susan E.; Croft, Simon L.; Yardley, Vanessa; Rock, Peter; Douglas, Kenneth T.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 25 p. 8087 - 8097
反应条件
1: sodium hydroxide / methanol / 4 h / 20 °C
2: ammonium chloride; zinc / water; methanol; tetrahydrofuran / 3 h / 20 °C
View Scheme
参考文献
ALLERGAN, INC.; YUAN, HAIQING; BEARD, RICHARD L.; LIU, XIAOXIA; DONELLO, JOHN E.; VISWANATH, VEENA; GARST, MICHAEL E.
Patent: US2013/231338 A1, 2013 ;
