2-(1-苯基乙基)苯酚合成路线 （共 31 条）
反应条件
[1-butyl-3-methylimidazolium][FeCl4] in nitromethane
T=80°C; Friedel-Crafts type benzylation; 12 h; regioselective reaction;
参考文献
Gao, Jian; Wang, Jin-Quan; Song, Qing-Wen; He, Liang-Nian
Green Chemistry, 2011 , vol. 13, # 5 p. 1182 - 1186
反应条件
1: phenol With aluminium
T=140°C; 1 h;
2: styrene T=180 - 190°C; 5 h; Further stages. Further byproducts.;
参考文献
Mamedova; Farzaliev; Velieva; Babaev
Petroleum Chemistry, 2007 , vol. 47, # 1 p. 55 - 60
反应条件
1.1: 80 percent / NaH / tetrahydrofuran / 20 °C
2.1: (-)-sparteine; sec-BuLi / diethyl ether / -78 - -20 °C
2.2: 95 percent / diethyl ether / -78 - 20 °C
3.1: 75 percent / AlI3 / acetonitrile / 12 h / Heating
View Scheme
参考文献
Wilkinson, James A.; Rossington, Steven B.; Leonard, John; Hussain, Nigel
Tetrahedron Letters, 2004 , vol. 45, # 28 p. 5481 - 5483
反应条件
1.1: (-)-sparteine; sec-BuLi / diethyl ether / -78 - -20 °C
1.2: 95 percent / diethyl ether / -78 - 20 °C
2.1: 75 percent / AlI3 / acetonitrile / 12 h / Heating
View Scheme
参考文献
Wilkinson, James A.; Rossington, Steven B.; Leonard, John; Hussain, Nigel
Tetrahedron Letters, 2004 , vol. 45, # 28 p. 5481 - 5483
参考文献
Ethyl Corporation
Patent: US3933927 A1, 1976 ;
反应条件
phenolated sodium
T=150°C;
参考文献
Okamoto,K. et al.
Bulletin of the Chemical Society of Japan, 1970 , vol. 43, # 5 p. 1545 - 1553
反应条件
1: pyridine / dichloromethane / 0 - 20 °C
2: [1-butyl-3-methylimidazolium][FeCl4] / nitromethane / 12 h / 80 °C
View Scheme
参考文献
Gao, Jian; Wang, Jin-Quan; Song, Qing-Wen; He, Liang-Nian
Green Chemistry, 2011 , vol. 13, # 5 p. 1182 - 1186
参考文献
Hart et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 4547,4549
反应条件
in water; acetonitrile
Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Huang, C.-G.; Shukla, Deepak; Wan, Peter
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5437 - 5442
反应条件
in water; acetonitrile
Irradiation; Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Huang, C.-G.; Shukla, Deepak; Wan, Peter
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5437 - 5442
